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Cytomegalovirus (CMV) is one of the most common human herpesviruses, infecting nearly half of the adult population in the US. Vertical transmission can occur during pregnancy, and congenital...
Loop-mediated isothermal amplification (LAMP) uses a stand-displacing DNA polymerase and four to six primers to rapidly amplify DNA at a single temperature. By eliminating temperature cyclin...
Gene Synthesis ensures fast access to nearly any DNA sequence, regardless of its origin or complexity. Its reliability, flexibility and fast turnaround time offer a clear advantage over trad...
Learning Objectives 1. Understand the life cycle of the malaria causing parasite, Plasmodium 2. Understand new approaches to identifying host regulators of infection 3. Describe advantages a...
Since its discovery in late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic of coronavirus disease 2019 (COVID-19). As of July of 2022, mo...
Recent outbreaks of Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed our limited therapeutic options for such diseases and our poor understand...
The COVID-19 pandemic has underlined the need for an efficient collaboration between scientists, policy makers and the general public to tackle the crisis. Infectious disease experts play a...
The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
Altered enteric microorganisms in concert with host genetics shape inflammatory bowel disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that eukaryotic vi...
Getting It Right: Preanalytical Impact on Coagulation Results Using a Case Study Approach According to published literature, up to 65% of errors occur in the preanalytical phase of laborator...
Critical in control of this pandemic is the ability to rapidly identify infectious individuals prior to their ability to infect others. With the introduction of better testing capacity and a...
This is a technical talk. Its objective is to provide details of virus sequencing, using SARS-CoV-2 as an example. Knowing the details, strengths, and limitations of virus sequencing will en...
Many clinically approved drugs that are prescribed to modulate human physiology are also potent antimicrobials at physiological concentrations. Recent systematic studies indicate that bacter...
Mammalian mucosal niches are colonized by a complex ecosystem of viruses, bacteria and fungi termed the microbiome. Unlike the gut microbiome, the vaginal microbiome is composed of small num...
Over 80% of opportunistic infections in humans are caused by microbial biofilms. Traditional methods of study for these infections have focused on single species yet there is a wealth of evi...
1. Identify the basic characteristics of the vaginal microbiota 2. Identify some ways in which the vaginal microbiota may protect against acquisition of sexually transmitted and urogenital i...
The vaginal microbiome is a critical component of female health. More than 30% of people with vaginas suffer from imbalances in the microbiome (e.g. bacterial vaginosis, yeast infections, an...
In all organisms, innate immune pathways sense infection and rapidly activate potent immune responses while maintaining a high degree of specificity to prevent inappropriate activation (auto...
Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis (Mtb) remains one of the leading causes of morbidity and mortality worldwide. This presentation will summarise the epidem...
Human intestinal epithelial cells (hIECs) are arranged as a monolayer of cells and provide the first line of defense against invading pathogens. Upon viral infection hIECs upregulate type I...
We live in a revolutionary era during which technology is leading to amazing advances in medicine. Parallel and aided by the development of artificial intelligence (AI) are the emergence of...
HIV-1 replicates in the body as a large viral population. Along with its high error rate during viral DNA synthesis and its short replication time (24 hours), the virus maintains sequence di...
Macrophages have been implicated in both the resolution and progression of influenza, but the drivers of these outcomes are poorly understood. We probed mouse lung transcriptomic datasets us...
Antibiotic treatment failure poses a burden on global public health systems. Bacteria can acquire mutations and extrachromosomal genes that allow them to be resistant to our existing drugs....
Date: August 31, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Antibodies are specialized proteins generated by an immune system in response to disease and infection. The staining ge...
Date: August 18, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Learning Objectives Discuss evolving etiologies for Community Acquired Pneumonia (CAP) Review the role of biomarkers in...
Date: August 16, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Physicians caring for expecting or pregnant mothers successfully manage pregnancy with the help of screening and diagno...