mouse monoclonal IgG1; Cdk2 Antibody (D-12) is an IgG1 κ mouse monoclonal Cdk2 antibody that detects Cdk2 of mouse, rat and human origin by WB, IP, IF and ELISA. Cdk2 Antibody (D-12) is available as the non-conjugated anti-Cdk2 antibody form, as well as multiple conjugated forms of anti-Cdk2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.