mouse monoclonal IgG2a; NFκB p52 Antibody (C-5) is an IgG2a κ mouse monoclonal NF kappa B p52 antibody (also designated NFKB p52 antibody, nuclear factor kappa B subunit 2 antibody, p100 antibody, or NFKB subunit 2 of nuclear factor-kappa-B (NFkB) transcription factor complex antibody) that detects the NF kappa B p52 protein of mouse, rat and human origin by WB, IP, IF and FCM. NFκB p52 Antibody (C-5) is available as both the non-conjugated anti-NF kappa B p52 antibody form, as well as multiple conjugated forms of anti-NF kappa B p52 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The NFκB transcription factor was originally identi-fied as a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino terminus of a precursor designated p105. A cDNA was isolated that encodes an alternative DNA binding subunit of NFκB. It is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFκB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.