JUN 12, 2022 8:00 AM PDT

Cannabis Users Need More Sedation During Gastric Endoscopy

WRITTEN BY: Kerry Charron

A presentation at the 2022 Digestive Disease Week showed evidence that cannabis consumers require higher levels of anesthesia in preparation for a gastric endoscopy. This diagnostic procedure involves inserting a small tube attached to a microscopic camera to capture images of the upper digestive tract. During the conscious sedation procedure, the patient is relaxed and comfortable but partially conscious with the help of anesthesia in order to minimize throat irritation and gag reflex caused by the inserted tube and camera scope. The study showed that cannabis users required an increased higher total sedation to achieve a state of ideal state of partial consciousness in order to provide a more comfortable diagnostic experience. 

The prospective cohort study included 419 adult outpatients undergoing endoscopic procedures. Each patient completed two questionnaires; one survey prior to the procedure about their cannabis use and another afterwards questionnaire about their awareness and comfort level during the procedure. Researchers analyzed questionnaire responses and details about the use of the sedatives midazolam, fentanyl, and diphenhydramine during the procedure. Increased sedation was defined as more than 5 mg of midazolam, more than 100 mcg of fentanyl, or the need for diphenhydramine. Although cannabis use was associated with a need for increased sedation for an endoscopy, it was not associated with higher use of sedation during a colonoscopy. Lead researcher Yasmin Nasser, M.D., Ph.D. explained that “patients didn't have increased awareness or discomfort during procedures, but they did require more drugs.” Future research will explore the mechanisms involved in the need for increased sedation for specific procedures. 

Disclosing cannabis use may be difficult for some patients given the historical stigma associated with cannabis use and its illegal status in many states but sharing cannabis use frequency and amount of cannabis use with health professionals is important. Discussing cannabis use with medical professionals is critical for developing safe anesthetic preparation. Physicians in states with legal cannabis are revising treatment plans that minimize medical procedure risks based for patients who use cannabis.  

Source: 

Eureka News Alert, 2022 Digestive Disease Week

 

About the Author
BA and MA in English, MPS in Human Relations, and Ed.D. in Higher Education Administration
Kerry Charron writes about medical cannabis research. She has experience working in a Florida cultivation center and has participated in advocacy efforts for medical cannabis.
You May Also Like
JUL 07, 2022
Cannabis Sciences
HHC, the latest cannabinoid
JUL 07, 2022
HHC, the latest cannabinoid
What is HHC? Read on to learn about the latest cannabinoid
JUL 28, 2022
Cannabis Sciences
FDA Approved Cannabis Drug Products
JUL 28, 2022
FDA Approved Cannabis Drug Products
The FDA has approved some cannabis infused drugs for medical usage. Here's what they are.
AUG 12, 2022
Cannabis Sciences
Study Shows Water Soluble CBD Has Better Absorption than Oil-Based CBD Products
AUG 12, 2022
Study Shows Water Soluble CBD Has Better Absorption than Oil-Based CBD Products
Colorado State University researchers examined the pharmacokinetics of cannabidiol (CBD) and its impact on liver functio ...
AUG 21, 2022
Cannabis Sciences
Synthetic Cannabinoid Poisonings Decrease as More States Legalize Cannabis
AUG 21, 2022
Synthetic Cannabinoid Poisonings Decrease as More States Legalize Cannabis
Synthetic cannabis, also known as Spice, AK-47 or K2, has received extensive news coverage after overdoses and deaths in ...
NOV 17, 2022
Cannabis Sciences
Most Common Side Effects from Consuming Too Much Weed
NOV 17, 2022
Most Common Side Effects from Consuming Too Much Weed
What happens when you ingest too much THC? Whether you smoke, vape, or consume edibles, here's what to expect
DEC 02, 2022
Cancer
No Evidence that Cannabis Relieves Symptoms in Advanced Cancer Patients
DEC 02, 2022
No Evidence that Cannabis Relieves Symptoms in Advanced Cancer Patients
Palliative care describes a class of healthcare intended to enhance patients' quality of life with severe, life-thre ...
Loading Comments...