JAN 13, 2021 2:45 PM PST

Antibody Can Target Dengue Viral Proteins

WRITTEN BY: Nouran Amin

Researchers have found an antibody that can stop the spread of the dengue virus—a mosquito-borne pathogen that infects 50 to 100 million people a year. Some of the symptoms of the virus includes fever, vomiting, muscle aches. It may lead to serious illness requiring long-term hospitalization and even in some cases fatal.

The dengue virus utilizes a particle protein called Non-Structural Protein 1 (NS1) that latches on the protective cells of organs and weakening the natural protective barrier. This allows virus to infect cells causing the rupture of blood vessels.

Learn more about the dengue virus:

However, the research shows that the antibody referred to as 2B7 will physically block the activity of NS1. It is effective against all four strains of the dengue virus.

"Flaviviruses infect hundreds of millions of people a year, and tens of thousands die from the associated diseases," said Argonne's Bob Fischetti, group leader with the X-ray Sciences Division and life sciences advisor to the APS director. "Protein structures determined at the APS have played a critical role in the development of drugs and vaccines for several diseases, and these new results are key to the development of a potentially effective treatment against flaviviruses."

Source: Science Daily

About the Author
  • Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
MAY 13, 2021
Immunology
Salmonella Vaccine Uses "Molecular Telephones" to Talk to the Immune System
MAY 13, 2021
Salmonella Vaccine Uses "Molecular Telephones" to Talk to the Immune System
Salmonella infections are a massive problem—Over 95 million people are affected by this foodborne illness every ye ...
MAY 19, 2021
Drug Discovery & Development
Combination Immunotherapy Shows Promise in Treating HIV
MAY 19, 2021
Combination Immunotherapy Shows Promise in Treating HIV
  Researchers have found that a new combination immunotherapy, alongside antiretroviral therapy (ART), is effective ...
JUN 04, 2021
Drug Discovery & Development
Scientists Identify 90 Drugs that Could be Repurposed to Fight COVID-19
JUN 04, 2021
Scientists Identify 90 Drugs that Could be Repurposed to Fight COVID-19
Researchers from The Scripps Research Institute in California have identified 90 drugs that could be repurposed for trea ...
JUN 22, 2021
Neuroscience
Virtual Reality Game Provides Pain Relief for Children
JUN 22, 2021
Virtual Reality Game Provides Pain Relief for Children
Researchers led by Ohio State University have found that smartphone-based virtual reality (VR) games can relieve pain fr ...
JUL 11, 2021
Drug Discovery & Development
Antibiotic Resistance May Be Passed Between Dogs and Owners
JUL 11, 2021
Antibiotic Resistance May Be Passed Between Dogs and Owners
Household pets may act as a reservoir for mcr-1, a gene that is resistant to a last-resort antibiotic, colistin. The fin ...
AUG 01, 2021
Drug Discovery & Development
New Compound Halts Neurodegeneration in Alzheimer's
AUG 01, 2021
New Compound Halts Neurodegeneration in Alzheimer's
Chemists have synthesized new compounds that can halt neurodegeneration linked to Alzheimer’s and other neurologic ...
Loading Comments...