JAN 13, 2021 2:45 PM PST

Antibody Can Target Dengue Viral Proteins

WRITTEN BY: Nouran Amin

Researchers have found an antibody that can stop the spread of the dengue virus—a mosquito-borne pathogen that infects 50 to 100 million people a year. Some of the symptoms of the virus includes fever, vomiting, muscle aches. It may lead to serious illness requiring long-term hospitalization and even in some cases fatal.

The dengue virus utilizes a particle protein called Non-Structural Protein 1 (NS1) that latches on the protective cells of organs and weakening the natural protective barrier. This allows virus to infect cells causing the rupture of blood vessels.

Learn more about the dengue virus:

However, the research shows that the antibody referred to as 2B7 will physically block the activity of NS1. It is effective against all four strains of the dengue virus.

"Flaviviruses infect hundreds of millions of people a year, and tens of thousands die from the associated diseases," said Argonne's Bob Fischetti, group leader with the X-ray Sciences Division and life sciences advisor to the APS director. "Protein structures determined at the APS have played a critical role in the development of drugs and vaccines for several diseases, and these new results are key to the development of a potentially effective treatment against flaviviruses."

Source: Science Daily

About the Author
  • Nouran earned her BS and MS in Biology at IUPUI and currently shares her love of science by teaching. She enjoys writing on various topics as well including science & medicine, global health, and conservation biology. She hopes through her writing she can make science more engaging and communicable to the general public.
You May Also Like
NOV 18, 2020
Drug Discovery & Development
Hepatitis C Drugs May Be Involved Coronavirus Treatment
NOV 18, 2020
Hepatitis C Drugs May Be Involved Coronavirus Treatment
At the present moment, there are no inhibitors that target protease activity of the novel SARS-CoV-2. The main proteases ...
DEC 01, 2020
Drug Discovery & Development
Breakthrough Drug Reduces Inflammation and Pain in Arthritis
DEC 01, 2020
Breakthrough Drug Reduces Inflammation and Pain in Arthritis
Researchers from the Universities of Oxford and Birmingham in the UK have found that otilimab can reduce infla ...
DEC 27, 2020
Drug Discovery & Development
Attacking Mitochondria in Tumors
DEC 27, 2020
Attacking Mitochondria in Tumors
Researchers found that attacking a cell’s mitochondria can starve cancer cells. The study involves a possible ther ...
JAN 13, 2021
Drug Discovery & Development
Could Rotten Egg Gas Reverse Alzheimer's?
JAN 13, 2021
Could Rotten Egg Gas Reverse Alzheimer's?
Researchers from Johns Hopkins University have found that hydrogen sulfide, a gas that smells like rotten eggs, may prot ...
FEB 02, 2021
Genetics & Genomics
Using Genetic Tools to Find Treatment Options for PTSD
FEB 02, 2021
Using Genetic Tools to Find Treatment Options for PTSD
With genome-wide association studies, researchers have been able to link small variations in the genome to a greater (or ...
FEB 06, 2021
Cannabis Sciences
Cannabis Reduces Disruptive Behavior in 50% of Young People with Autism
FEB 06, 2021
Cannabis Reduces Disruptive Behavior in 50% of Young People with Autism
Current pharmacotherapies for disruptive behaviors among those with autism are relatively ineffective. Now though, resea ...
Loading Comments...