JUL 29, 2020 3:00 PM EDT

Advances and trends enabling the growth of immune-based cancer research and therapeutics

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Associate Vice President, Agilent Cell Analysis
    Biography



      David Ferrick began his career as a University of California professor, then entrepreneur and currently industry executive focused on life sciences tools, drug discovery and diagnostics specifically in the areas of immunology and cancer. He has commercialized many life science products into new and emerging markets based on nascent technologies and advanced several drug screening programs from target identification to preclinical testing. He has authored over 150 peer reviewed publications and 13 patents along with several book chapters. Dr. Ferrick received his Ph.D. in Microbiology and Immunology from Georgetown University in Washington D.C.


    Abstract

    With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of the need to understand the interplay within the tumor microenvironment between tumor malignancy and protective immunity. Targeting the liabilities of tumors by ‘tuning’ cellular networks back into homeostatic harmony may just be the key to effective, durable therapies.

    Targeting and eliminating pathogenic cells is not good enough on its own to consistently achieve long-term survival. For example, immune cells that can eliminate tumors must persist in hostile, immunosuppressive microenvironments throughout tumor elimination and be capable of renewing protective surveillance. With the emergence of quantitative, live-cell analysis platforms researchers can make the necessary sensitive, time-resolved measurements to monitor the temporal components of an ever evolving cellular network.

    This talk will showcase new concepts and strategies to target cancer through an understanding of the immune response. We will discuss purpose-built applications that enable real-time measures of immune cell function, fate and fitness. This tool bench provides the capability to measure, engineer and control immune cell function, thus enabling translational researchers and developers to achieve the necessary level of therapeutic potency and safety

     

    Learning Objectives:

    1. Define new concepts and understanding of the interplay between tumors and immunity

    2. Identify new solutions to model and study tumor immunity over time

    3. Key strategies being tested to target tumor liabilities through immune-based drug design


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