Staff Scientist, Bioinformatics, Thermo Fisher Scientific
BIOGRAPHY
AUG 16, 2018 8:00 AM PDT
Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
Speaker
Event Date & Time
DATE: August 16, 2018
TIME: 08:00AM PDT
TIME: 08:00AM PDT
Abstract
Immuno-Oncology Webinar Series (#2 of 3)
This webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards predictive and mechanistic biomarker discovery for cancer immunotherapy. Dr. Looney will focus on immunotherapy biomarker applications of a long-amplicon TCRB sequencing assay which provides coverage of the CDR1, 2 and 3 regions of the rearranged TCRB chain. He will highlight recent data from individuals receiving checkpoint blockade immunotherapy for cancer which suggest that long-amplicon TCRB repertoire sequencing of pre-treatment peripheral blood may be used to identify predictive biomarkers for immune-mediated adverse events and objective clinical response.
Learning Objectives:
- Understand current applications of T cell receptor sequencing to immunotherapy translational research.
- Describe the advantages of long-amplicon TCRB sequencing via Ion Torrent for immunotherapy biomarker discovery from peripheral blood.
Register for our 3 Part Series here:
- #2 - Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
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Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
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