DEC 18, 2020 5:00 AM PST

A new approach of COVID-19 surveillance testing to maximize the identification of asymptomatic patients

Sponsored by: DiaSorin
C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Associate Professor and Head of the Unit of Microbiology The Greater Romagna Area Hub Laboratory DIMES - University of Bologna
    Biography

      Prof. Sambri graduated summa cum laude in Medicine at the Alma Mater Studiorum, the University of Bologna, in 1986. From September 1st, 1988 to May 31st, 1989 he attended the Laboratory of the ID Division, the University of California at Los Angeles under the supervision of Michael A. Lovett working on genetic transformation of spirochetes. He received his Ph.D. degree in Microbiology from the University of Genoa in 1991, discussing a thesis on the microbiology of spirochetal infection. From 1991 to 2004 he worked as research associate in the Laboratory of the Section of Microbiology, DMCSS, the University of Bologna. Presently he holds a position as Associate Professor of Medical Microbiology and Head of the Laboratory of the Regional reference Centre for Emerging Infections, the University of Bologna. The research work refers to spirochetes and chlamydiae. From September 2003, Dr Sambri holded also the position of Head of the Regional Reference Centre for Emerging Infectious Disease (CRREM) and in this field he has been recently involved in the research and diagnostic work related to the outbreak of Chikungunya fever and West Nile virus that hit the Emilia Romagna Region during the recent years. Since December 2012 Dr Sambri holds the position of Head and Director of the Unit of MIcrobiology - The Great Romagna Hub laboratory. His work resulted in more than 200 scientific publications in international Journals. Dr Sambri was selected as a reviewer for many Journals, including Clinical Infectious Diseases, The Journal of Infectious Diseases and the Journal of Infection. Vittorio Sambri is member of the EU funded research project PREDEMICS and of the SAB of the EU funded research project VECTORIE. He is the PI of the research project "New and emerging vector borne infectious diseases in Italy: epidemiology, surveillance, diagnosis and impact on the safety of blood and organ donations" funded by the Italian Ministry of Health.


    Abstract

    Date:  December 18, 2020

    Time: 5:00am PST, 2:00pm CET

     

    Europe continues to battle a second wave of COVID19 epidemic; more than 30.000 newly infected patients are being confirmed daily in Italy. As of November 16th, 27,687 individuals have been infected with SARS-CoV-2 in Italy, of whom 600 have passed away. The World Health Organization (WHO) has raised a global warning and announced the need for a test system for COVID-19- suspected patients (World Health Organization, 2020). SARS-CoV-2 is known to be spread even by infected people who experience only mild symptoms or are asymptomatic carriers (Li etal.,2020;Baietal., 2020; Rothe et al., 2020). Therefore, there is a need to expand testing capacity also to asymptomatic individuals to stop transmission. In routine clinical practice, SARS-CoV-2 infection is determined by reverse-transcription PCR (RT-PCR) analysis (Corman et al., 2020). The RT-PCR test is conducted using different types of specimens, including sputum, nasopharyngeal swabs, pharyngeal swabs, saliva, stool, bronchoalveolar lavage fluid, and endotracheal aspirate fluid (KK-W et al., 2020; To et al., 2020; Wang et al., 2020). However, the RT-PCR test is not rapid (it typically takes 3–4 h for results), and it requires specialized laboratory equipment and skilled technicians, while antigen tests are simple and can be performed routinely in clinical laboratories (Lai et al., 2020; Clerc and Greub, 2010). New more cost-effective and high throughput test system will be important for preventing viral spread and monitoring infection levels in COVID-19 patients. Here, we are presenting a newly approach of Covid-19 testing that will be used as a filter, by identifying, isolating, and thus filtering out currently infected persons, including those who are asymptomatic. This is a new regimen of testing to detect frequently the asymptomatic infected persons, which are primary source of transmission.

     

    Learning Objectives:

    • To assess the use of Antigen assay in screening of asymptomatic COVID-19 individuals
    • To demonstrate the impact of a new regimen of COVID-19 testing
    • To evaluate whether the new screening approach is cost-effective

     

     

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    A new approach of COVID-19 surveillance testing to maximize the identification of asymptomatic patients

    Sponsored by: DiaSorin
    C.E. Credits: P.A.C.E. CE Florida CE

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