DEC 05, 2019 5:00 AM PST

The clinical implications of high sensitive assays for HBsAg

Sponsored by: Abbott
C.E. Credits: P.A.C.E. CE Florida CE
Speaker

Abstract
DATE:  December 5, 2019
TIME:   5:00am PST, 8:00am EST
 
The diagnosis of an active infection by the hepatitis B virus (HBV) relies on testing for the HBV surface antigen (HBsAg). Over the decades the sensitivity of HBsAg assays has increased, and the most recent solutions attain a level of 5 mIU/mL and enable to detect active HBV also at very low level of expression, with HBV-DNA levels <100 mIU/mL. The availability of such assays will help improve the safety of blood screening in settings that do not encompass testing for HBV-DNA and will enable unveiling HBsAg in a substantial share of "occult" or "latent" HBV infections (OBI). Unveiling OBIs has a great clinical relevance in immunocompromised or immunosuppressed patients and in people coinfected by other viruses, such as HCV or HIV. Additionally, since the negativity for HBsAg is a major endpoint for antiviral treatment with nucleosi(t)ide analogues, a higher sensitivity for HBsAg can help with a safer interruption of treatment.
 
Learning Objectives:
  • Review the natural history of HBV infection and the progress in HBsAg testing
  • Understand the mechanism and clinical implications of HBV reactivation
  • Acknowledge the medical improvements linked to a better sensitivity for HBsAg
 
 
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LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

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DEC 05, 2019 5:00 AM PST

The clinical implications of high sensitive assays for HBsAg

Sponsored by: Abbott
C.E. Credits: P.A.C.E. CE Florida CE

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