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The detection, characterization, and surveillance of the SARS-CoV-2 viral genome using hybridization capture-based NGS assay

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Chief Medical Officer, Biotia, Research Assistant Professor, Department Cell Biology/College of Medicine, SUNY Downstate Health Sciences University
    Biography
      Dorottya earned her MD and PhD in clinical medicine from Semmelweis University of Medicine in Hungary. Holding postdoctoral fellowships at Baylor College of Medicine/Texas Children's Hospital and Columbia University, she has 10+ years of experience in translational medicine, pediatrics, gastroenterology, microbiology, and clinical metagenomics. She led cutting-edge clinical trials on fecal microbiome transplantation and developed a multicenter research program to understand the role of the gut-brain axis in the integrative neuroscience field. Currently, Dorottya is the Chief Medical Officer at Biotia, a NYC-based startup focusing on rapid infectious disease diagnostics, surveillance, and prevention of hospital-acquired infections powered by artificial intelligence.

    Abstract

    As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) became a tool to diagnose infectious diseases. The rapid identification of pathogens providing key information on species, strains, genetic variants and geographic origin, NGS and artificial intelligence-based approach enables emerging pathogen and strain identification, patient risk stratification, AMR tracking, clinical interpretation and outcome prediction.

    Learning Objectives:

    1. Understanding the next-generation sequencing (NGS) and how NGS can be used to fight against infectious diseases and the current pandemic

    2. Facilitate in-depth knowledge about harnessing microbial genetic information to develop breakthrough diagnostic and surveillance tools

    3. Leverage insights gathered from the microbiome and virome to fight against infectious diseases through the development of precision diagnostics

    4. Understanding how NGS and the SARS-CoV-2 viral genome can be used for pandemic surveillance


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