The Future of Antibody Drug Discovery: From Target Validation to Candidate Selection

This webinar will provide an overview of the antibody discovery process highlighting the critical steps involved in developing effective antibody-based therapeutics. The goal is to guide the audience through the different stages of antibody drug discovery, shedding light on the latest advancements, methodologies, and challenges encountered along the way. In addition, the webinar will cover Benchling’s Antibody Solution Accelerator, a set of ready to use configurations necessary to capture the process of drug discovery.

 

The audience will come away with an understanding of the following critical elements and how Benchling’s Antibody Solution Accelerator can support them:

• Target Identification: The crucial step of identifying and validating specific molecular targets that play a role in disease pathogenesis.
• Screening: Methods to identify potential antibody candidates.
• Hit Generation: Strategies employed to generate antibody hits with desirable binding properties.
• Lead Selection: Criteria and assays used to assess factors such as binding affinity, specificity, stability, and pharmacokinetic properties to choose the most suitable leads for further development.
• Lead Optimization: Lead antibodies are modified to enhance their therapeutic potential. Explore techniques like antibody engineering, affinity maturation, and antibody humanization to improve properties such as stability, efficacy, and manufacturability.
• In Vivo Safety & Efficacy: Assessing the performance of the antibody in mice and other model organisms.