GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)

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Abstract

GeoMx Digital Spatial Profiling Technology! This leading digital technology offers multiplexed measurement of protein and nucleic acids with an unparalleled level of precision. Quantify 10's-10,000's of targets (RNA or protein) on a fresh frozen or formalin-fixed, paraffin-embedded (FFPE) tissue section in a completely non-destructive manner. The newly launched GeoMx Cancer Transcriptome Atlas (CTA) is designed for comprehensive profiling of the tumor biology, tumor microenvironment, and the immune response. Profile the RNA expression over 1,800 genes simultaneously with spatial resolution in any region of interest from a single tissue section using the GeoMx Digital Spatial Profiler.

Learning Objectives:

1. Define spatial genomics and it's advantage over gene expression approaches

2. Understand the GeoMx workflow and resulting data

3. Explain its application to immune oncology


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