New Guidance for Investigation of Vitamin B12 Deficiency: Considerations for Transitioning to Appropriate Testing

The signs and symptoms of vitamin B12 deficiency are many but both variable and hard to identify as B12 deficiency¹. Anaemia and macrocytosis may be late findings or never appear, especially if the patient has either iron deficiency or is being supplemented with folate². Many patients may have B12 deficiency for years without being diagnosed, yet the early diagnosis of B12 deficiency is crucial to prevent irreversible neurologic damage^3,4.

 

1. Sands et al Vitamin B12 deficiency: NICE guideline summary  BMJ 2024;385:q1019
2. Green Vitamin B12 deficiency from the perspective of a practicing hematologist Blood First Edition paper, 30 March 2017 https://ashpublications.org/blood/article/129/19/2603/36140/Vitamin-B12-deficiency-from-the-perspective-of-a
3. Hooper et al Patient journeys: diagnosis and treatment of pernicious anaemia British Journal of Nursing, 2014, Vol 23, No 7
4. Devalia, Malloy, Hamilton British Journal of Haematology, 2014, 166, 496–513

 

In this webinar Prof. Dominic Harrington, Chief Scientific Officer, Synnovis will share his insights on vitamin B12 deficiency , about newer tests such as Active B12 and its role in earlier diagnosis, and impact on patient management.

 

 

Learning Objectives