HbA1c: The Hidden Factors - Biological Interferences

Date:  June 15, 2021

Time: 9:00am PDT

HbA1c is routinely used in the clinical laboratory to diagnose and monitor diabetes mellitus. Many methods have been standardized to provide precise and accurate results for normal patients. For the other common Hb variants, most of the methods are now relatively free of analytical interference. 

This session explains the clinical value of HbA1c in individual patient care; when an analytically correct result provides clinically misleading information due to red cell/hemoglobin lifespan. Hemoglobinopathies (variants & thalassemia’s), as well as anemia, iron deficiency and genetic variation impact the red blood cell/hemoglobin lifespan and potentially the glycation rate of hemoglobin. How should these patients be identified and managed so the best care can be provided to the patient? How can your laboratory help?

Join us for part 2 of the Sebia webinar series to learn more about the hidden factors – biological interference on HbA1c.

Learning Objectives:

• Identify components contributing to glycation rate of Hb to form HbA1c
• Discuss which conditions can cause an artificial decrease/reduction in the levels of circulating HbA1c
• Review which conditions should prevent the use of HbA1c for monitoring/diagnosing diabetic patients
• Identify methods that indicate the presence of clinically significant hemoglobinopathies and/or thalassemia’s

Webinars will be available for unlimited on-demand viewing after live event.