High-Content Phenotypic Screening - Answering Questions You Haven't Even Asked Yet

High-content (HC) phenotypic profiling approaches are a powerful tool to study the effect of biological, genetic, and chemical perturbations on cells. This increasingly popular method allows scientists to obtain detailed cellular profiles, consisting of hundreds of morphological features - measures of intensity, shape, size, etc. These approaches are applied in a wide range of studies, from drug discovery to functional genomics screening. Many scientists, however, do not have access to the tools or knowledge required to analyze these rich multiparametric datasets, resulting in many HC datasets being under-utilized, or even avoided.

 

This webinar will introduce viewers to the general concept of HC approaches, illustrated using a Cell Painting experiment. Moreover, we will demonstrate a robust and reproducible data analytics workflow to transform these rich and complex datasets into biological insight.