Use of host-response serum biomarkers to distinguish bacterial from viral infections

In the emergency department, distinguishing between bacterial and viral infections can be challenging, leading to inappropriate use of antibiotics that may contribute to the development of bacterial antibiotic resistance.  Humans mount immune responses to bacteria and viruses that are qualitatively and quantitatively different.  These differences can be exploited to distinguish between these types of infection, which is important in choosing the correct therapy for the patient. In this webinar we will review recent advances in the development and validation of host-response biomarkers for the diagnosis of bacterial and viral infections.  We will then present several case studies in which a new test measuring serum CRP, IP-10 and TRAIL successfully identifies the bacterial or viral etiology of infection. 

 

Learning Objectives