MENU
FEB 23, 2022 1:30 PM PST

Innovative Approaches to Biomarker Discovery in the Drug Development Process

Sponsored by: NanoString Technologies
C.E. Credits: P.A.C.E. CE Florida CE
Speaker

Abstract

High-throughput sequencing technology such as RNASeq and whole genome sequencing has enabled deep characterization of health and disease states.  Biomarker discovery by these means has only had limited success translating to the clinic.  While these disease specific biomarker discoveries in cancer have been proven actionable, the magnitude of response to the indicated therapy tends to be variable across different patients and a portion of these patients ultimately develop drug resistance.  As such, robust biomarker discovery and development strategies are essential in the drug development process – not only to identify new therapeutic targets and identify patients that are likely to respond to therapy, but also identify patients that are likely to develop drug resistance.  Spatial biology technology, such as NanoString’s GeoMx, presents a unique opportunity for biomarker discovery in the drug development process and this type of biomarker discovery approach will be the focus of this presentation.

For research use only.  Not for use in diagnostic procedures.
 

Learning Objectives:

1. Identify challenges associated with biomarker discovery.

2. Discuss what spatial biology is, and why it is gaining so much attention right now.

3. Explain the unique benefits spatial biology can provide for biomarker discovery.


Show Resources
You May Also Like
MAY 17, 2022 9:00 AM PDT
MAY 17, 2022 9:00 AM PDT
Date: May 17, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Gene therapeutics have great potential to treat many severe diseases in an unprecedented, targeted manner. The biopharmace...
JUN 21, 2022 6:00 AM PDT
JUN 21, 2022 6:00 AM PDT
Date: June 21, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CEST) The global understanding and practice of medicine is currently undergoing a revolutionary change. This shift to precision...
APR 28, 2022 8:00 AM PDT
APR 28, 2022 8:00 AM PDT
Date: April 28, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Human pluripotent stem cells (PSCs) and their derivatives hold great potentials in...
JUN 29, 2022 8:00 AM PDT
JUN 29, 2022 8:00 AM PDT
Date: June 29, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CEST) As of May 2022, there have been more than 500 million confirmed cases of COVID-19, including numerous variants. Additiona...
MAY 24, 2022 11:00 AM PDT
MAY 24, 2022 11:00 AM PDT
Date: May 24, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 7:00pm (CEST) NGS tumor profiling has become the mainstay of modern cancer therapy. Several NCCN-guided and FDA-approved therapies are c...
MAR 16, 2022 8:00 AM PDT
C.E. CREDITS
MAR 16, 2022 8:00 AM PDT
Date: March 16, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CET) Handling of potent and/or hazardous substances is commonplace in sev.....
Loading Comments...
Show Resources