Leveraging acoustic and tip-based liquid handling to increase SARS-CoV-2 sequencing throughput

Date:  June 29, 2021

Time: 08:00am PDT

As the SARS-CoV-2 virus that causes COVID-19 keeps mutating, there is a growing need to sequence the viral genome from many COVID-19-positive samples to better understand the genetic sequence of the virus. Identification of viral variants enables the development of diagnostic tests and therapeutics against the virus. Sequencing viral variants requires high- throughput sequencing methods. The ideal protocol would have a low-cost, high-throughput and simple workflow compatible with a wide variety of sequencing instruments. To address this need we discuss a method deployed on the Beckman Coulter Life Sciences tip-based and acoustic liquid handling platforms to process samples in batches of 384 samples. The protocol can be completed in a single shift and uses only three tips per sample.

Biomek i-Series and Echo products are for research use and not intended or validated for use in the diagnosis of disease or other conditions. © 2021 Beckman Coulter, Inc. All rights reserved. Beckman Coulter, the stylized logo, and the Beckman Coulter product and service marks mentioned herein are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. Echo is a trademark or registered trademark of Labcyte Inc. in the United States and other countries. Labcyte is a Beckman Coulter company. All other trademarks are property of their respective owners. 21.05.1712 AUTO

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