Infectious diseases, such as COVID-19, are challenging to study in animal models due to species differences, and conventional 2D cell-based systems lack the complexity to appropriately model the disease or immune response in humans. Organs-on-Chips offer a human relevant system that can recreate key disease phenotypes in a more physiological microenvironment due to their complex 3D architecture and mechanical forces induced by flow and stretch. In this webinar, we discuss how the Airway Lung-Chip and Alveolus Lung-Chip can be used to study viral infection and accelerate the development of new therapeutics.
Learning Objectives:
1. Learn how Organs-on-Chips technology can be applied to recreate key aspects of pulmonary physiology, specifically the creation of Airway and Alveolus Lung-Chip models
2. Review data demonstrating how the Airway Lung-Chip can be used to study viral infection and evaluate the efficacy of therapeutic interventions