IHC Specialist, Cell Signaling Technology
BIOGRAPHY
OCT 03, 2018 9:00 AM PDT
Mechanisms of Myeloid Immunosuppression: Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
Speaker
Event Date & Time
DATE: October 3, 2018
TIME: 9:00am PDT, 12:00pm EDT
Abstract
Infiltrating myeloid cells constitute a significant component of the suppressive tumor microenvironment (TME) and possibly contribute to therapeutic failures. An understanding of the immune regulatory context of the TME is required to harness the power of the antitumor immune response. Here, we present solutions to better understand the TME in a context-dependent manner. Using highly validated antibodies, immunohistochemical techniques are employed in a seven-color TSA-based multiplex panel along with single and dual-plex chromogenic stains to visualize biomarker expression in an array of tumor types. Newly validated Arginase1 and IDO1 monoclonal antibodies add a functional readout of the immunosuppressive TME to phenotypic marker analysis.
Learning Objectives:
- Understand the importance of the immune regulatory context of the TME
- Learn about solutions to better understand the TME in a context-dependent manner
You May Also Like
DEC 10, 2024 | 9:00 AM
To-date, proteomic analysis has been severely limited in scale and resolution. Analyzing protein samples using an intact, single-molecule approach holds th...
OCT 02, 2024 | 7:30 AM
De novo gene synthesis and protein expression are established technologies that can give access to nearly any target DNA or protein sequence, allowing for engineering of biologics. In this p...
OCT 03, 2018 9:00 AM PDT
Share
Mechanisms of Myeloid Immunosuppression: Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
Loading Comments...