Professor of Pathology and Oncology, Associate Director, Molecular Diagnostics Laboratory, Johns Hopkins University School of Medicine
BIOGRAPHY
Speaker
Abstract
Dr. Eshleman will be discussing how MSI provides a functional readout of mismatch repair status, the implications of mismatch repair deficiency in cancer cells, and how elevated mutation rate associated with MSI-H tumor cells drive the production of neoantigens thought to contribute to immunotherapeutic response.
Learning Objectives:
• Recall implications of mismatch repair deficiency in solid tumors
• Define Key advantages of Long Mononucleotide Repeats (LMRs) in detecting microsatellite instability
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