NOV 04, 2020 8:00 AM PST

Overcoming barriers to productivity in HCS - An image-to-answer solution for biologists

Sponsored by: Cytiva
C.E. Credits: P.A.C.E. CE Florida CE
Speakers
  • Senior Product Manager, Cellular Analysis, Cytiva
    Biography
      Will Marshall has over 10 years of experience in the application of advanced microscopy techniques and digital image analysis. Prior to joining Cytiva, formerly part of GE Healthcare's Life Sciences business, he worked in a technology development core facility at the Stowers Institute for Medical Research. Here, he developed custom end-to-end data acquisition and analysis solutions with an emphasis on the use of automation to increase experimental throughput.
      As a Product Manager at Cytiva, Will is responsible for the continual development of products in the High Content Analysis portfolio. Currently, he and his teams are focused on developing novel analysis workflows that leverage machine learning and artificial intelligence methods to increase the efficiency and comprehensiveness of image-based high-throughput screens.
      Will graduated from the University of Missouri-Columbia with a degree in Biochemistry and currently works in Issaquah, Washington.
    • CEO & Cofounder, Core Life Analytics
      Biography
        David Egan is the co-founder and CEO of Core Life Analytics, a Netherlands-based company that helps biologists to analyze their own data. Born in Carrickerry, Ireland he completed his undergraduate training in Industrial Chemistry at the University of Limerick. He received his Ph.D. in 1997 from Cornell University Graduate School of Medical Sciences in New York, NY. His graduate thesis was carried out in the laboratory of Dr. Kathleen Scotto at Memorial Sloan Kettering Cancer Center.
        It was during a post-doctoral fellowship with Dr. Ron Evans at The Salk Institute in la Jolla, CA that David became interested in the use of high throughput technologies for drug discovery. This led to a position at OSI Pharmaceuticals in 2001 and, after a return to Europe in 2003, subsequent positions establishing and managing academic automation facilities at the Netherlands Cancer Institute in Amsterdam, and the University Medical Center Utrecht.
        In Utrecht, while managing the Cell Screening Core at the Department of Cell Biology that he encountered the challenges of data analytics in high throughput image-based screening. This led to the development of the StratoMineR platform with Wienand Omta and the subsequent establishment of Core Life Analytics, which was co-founded with Wienand in 2016.



      Abstract
      Date:  November 4, 2020
      Time: 8:00am (PDT),  11:00am (EDT)
       
      High-content screening (HCS) is widely used for research in quantitative cellular biology and has proven to be a valuable tool in drug discovery. The multi-step process of deriving answers from image data, however, remains complex and fraught with challenges limiting productivity. Cytiva and Core Life Analytics have partnered to offer an end-to-end software solution that addresses these challenges. By removing the need for specialized expertise, we have empowered research biologists to carry out their own data analysis. With an intuitive workflow-driven design, machine learning, and cloud computing, researchers can leverage cutting-edge image analysis and statistical data mining methods to improve assay sensitivity and shorten the time from image to answer.
       
      Learning Objectives
      • Review the importance of quality control in high-content screening and summarize best practices to minimize sources of error in the analysis pipeline
      • Describe the impact of improved segmentation accuracy on the overall endpoint of high content screens
      • Discuss how the “big data” problem can be addressed with cloud-based comprehensive statistical analysis and interactive data visualization
       
       
      Webinars will be available for unlimited on-demand viewing after live event.
       
      LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

      Show Resources
      You May Also Like
      SEP 10, 2020 9:00 AM PDT
      C.E. CREDITS
      SEP 10, 2020 9:00 AM PDT
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      NOV 16, 2020 8:00 AM PST
      C.E. CREDITS
      NOV 16, 2020 8:00 AM PST
      Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
      OCT 29, 2020 6:00 AM PDT
      C.E. CREDITS
      OCT 29, 2020 6:00 AM PDT
      Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
      NOV 10, 2020 7:00 AM PST
      C.E. CREDITS
      NOV 10, 2020 7:00 AM PST
      DATE: November 10, 2020 TIME: 7:00am PDT, 10:00am EDT Automation can provide tremendous benefits such as increased pipetting precision and accuracy, productivity, and throughput. Numerous wo...
      NOV 18, 2020 8:00 AM PST
      C.E. CREDITS
      NOV 18, 2020 8:00 AM PST
      DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
      AUG 18, 2020 10:00 AM PDT
      C.E. CREDITS
      AUG 18, 2020 10:00 AM PDT
      DATE: August 18, 2020 TIME: 10:00am PT Get deeper understanding of gene expression patterns by using assays that retain spatial organization at single cell resolution! Come learn about the n...
      Loading Comments...
      Show Resources
      Attendees
      • See more