When it’s time for researchers to pick a protein or formulation, the best ones need to sweat it out at elevated temperatures for extended periods of time. Thermal ramps are fast and give a lot of information like Tm and Tagg – but the full stability story also needs results from long-term isothermal tests.
Uncle is the first all-in-one biologics stability screening platform combining fluorescence, SLS and DLS that now also has you covered with a tailored toolkit of applications for isothermal experiments. Take the hassle out of collecting this critical info and monitor the behavior of your proteins over hours and days while they are stewing at constant temperatures. Streamline accelerated stability testing and start it as early as the candidate stage – Uncle only needs 9 µl of sample, which are securely sealed in quartz cuvettes for hours and days. For the longest tests, keep your Uncle free for other stability work with the new Out-Of-the-Box apps that let you run a days-long experiment without tying up the instrument.
Join our live event and learn how the new isothermal apps in Uncle combine with thermal ramps to give a more complete stability picture for model proteins in different formulations.