JUN 04, 2024 8:00 AM PDT

Relative Affinity Ranking of Recombinant Antigen-Specific Antibody Hits with Bruker's Beacon® Optofluidic System


Antibody affinity is a critical metric for antibody therapeutic development and is often only assessed after initial antibody discovery hit generation. However, due to the cost and throughput of small-scale antibody production, antibody affinity characterization is only reserved for a few lead candidates. Here, we demonstrate a high-throughput relative affinity ranking of recombinant antigen-specific antibodies during the antibody discovery workflow on Bruker’s Beacon optofluidic system.

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