NOV 12, 2020 6:00 AM PST

Standardization with Clinical Digital Pathology - The Ki-67 Case

Sponsored by: Visiopharm®
C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Clinical Development Engineer, Data Lead
    Biography

      Dzenita is a Clinical Development Engineer at Visiopharm. She holds a M.Sc. in Biomedical Engineering with a focus on medical image analysis from the Technical University of Denmark. Over the last 5 years, she has been involved in the development of CE-IVD APPs for the Visiopharm software platform, including data sourcing and management, and she specializes in external collaborations and projects with a clinical/CE-IVD/FDA scope.


    Abstract

    The nuclear proliferation biomarker Ki-67 has multiple potential roles in breast and other cancers, both as a prognostic but also predictive marker. However, several studies have shown that the assessment of Ki-67 with immunohistochemistry (IHC) suffers from both intra-and inter-observer variability and low reproducibility. On top of that it is still being debated what the most appropriate way of scoring Ki-67 IHC is - should one use global scoring or the hot spot scoring method? In this webinar we will look into how Visiopharm CE-IVD APPs can be used for standardizing the assessment of Ki-67 IHC. We will also show how the APPs can accommodate both the global scoring method and the hot spot scoring method allowing for a tailored solution that fits the diagnostic workflow in your laboratory. We will focus on the clinically validated APPs, but will also reveal some of the AI technologies we have for research use.

    Learning Objectives:

    1. Understand the limitations of manual biomarker assessment in image analysis

    2. Learn how CE-IVD APPs can used for standardization of Ki-67 scoring

    3. Get a glimpse of the future AI-powered workflows for biomarker analysis


    Show Resources
    You May Also Like
    SEP 10, 2020 9:00 AM PDT
    C.E. CREDITS
    SEP 10, 2020 9:00 AM PDT
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    NOV 18, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 18, 2020 8:00 AM PST
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    AUG 25, 2020 8:00 AM PDT
    C.E. CREDITS
    AUG 25, 2020 8:00 AM PDT
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    DEC 15, 2020 10:00 AM PST
    C.E. CREDITS
    DEC 15, 2020 10:00 AM PST
    DATE: December 15, 2020 TIME: 10:00am PST Scientists from Thermo Fisher Scientific will walk us through the world of microorganisms. They will discuss their most recent research on viruses,...
    NOV 16, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 16, 2020 8:00 AM PST
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    OCT 29, 2020 6:00 AM PDT
    C.E. CREDITS
    OCT 29, 2020 6:00 AM PDT
    Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
    Loading Comments...
    Show Resources