THUNDER - Revealing Image Detail Hidden in the Haze

 

In widefield fluorescence microscopy both the contrast and resolution of a captured image is corrupted by light collected from adjacent planes, scattered light, camera sensor noise and the system’s point spread function. These contributions result in increased image haze/blur, obscuring the image details. Leica Microsystems THUNDER technology addresses these pitfalls through computational clearing and adaptive deconvolution. Together these methods improve image contrast and resolution beyond that of a typical high-end widefield fluorescence microscope.

 

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