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MAR 23, 2013 8:00 AM PDT

Development and Production of Viral Vectors: Advances in Processes and Translation for Human Gene Therapy

Speaker
  • Director of Aseptic Processing Laboratories and Research Viral Vector Core Director of Cincinnati Children's Hospital
    Biography
      The Clinical Vector Core at The Children's Hospital of Philadelphia (CHOP) is a division of the Center for Cellular and Molecular Therapeutic). Dr. van der Loo directs the manufacturing of viral vectors in support of pre-clinical GLP studies and early phase clinical trials. The laboratory has a strong track record in the manufacturing of AAV (Serotypes 1, 2, 5, 6, 8 and 9) and lentiviral vector. Additional services include manufacturing of clinical excipient, CMC support, and vector stability.

    Abstract
    Dr. Johannes van der Loo will cover the vital role viral vectors play in today's gene research, as well as the use of ultracentrifugation to produce these key delivery systems.

    Learning Objectives:
    • Understand the vital role viral vectors play in today's gene research
    • Understand the use of ultracentrifugation to produce these key delivery systems

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