Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded proteins. The histopathological hallmark of synucleinopathies is the deposition of ɑ-...
Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
Over 40 tandem repeats undergo expansion events that lead to neurological disease. This number is likely an underestimate as many repeats are difficult to amplify using existing short read s...
Adolescence is a critical period for the developing brain, and binge drinking during this neuromaturation can result in enduring abnormal brain function and behavior. Repeated adolescent bin...
Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in society, no cur...
One role of theory is in guiding future experiments: What should we aim to measure? Which experimental results should we be surprised about? I will argue here that simple random networks mod...
Multiscale modeling has arisen as a focus of computational systems biology, with the realization that genome, proteome, connectome, etceteromes, will only become comprehensible once placed i...
Recent advances in machine learning have shown that deep neural networks (DNNs) can provide powerful and flexible models of neural sensory processing. In the auditory system, standard linear...
Complex behaviors are often driven by an internal model, which integrates sensory information over time and facilitates long-term planning to reach subjective goals. {\color{rev}A fundamenta...
The intrinsic activity of the brain is organized into networks and motifs that vary over time. To understand how coordinated macroscale patterns of intrinsic activity flow across the brain&r...
Targeted stimulation of the brain has the potential to treat mental illnesses but designing an appropriate protocol requires a multitude of choices. I will describe an approach to help desig...
Threshold-linear networks (TLNs) display a wide variety of nonlinear dynamics including multistability, limit cycles, quasiperiodic attractors, and chaos. Over the past few years, we have de...
Cortical circuits often receive multiple inputs from upstream populations with non-overlapping stimulus tuning. Both the feedforward and recurrent architectures of the receiving cortical lay...
Learning Objectives: 1. Explore the neuroinvasive potential of SARS-CoV-2 2. Learn about possible consequences of neuroinvasion of SARS-CoV-2 3. Identify neuroimmune responses against SARS-C...
Understanding how populations of neurons work together to represent stimuli, build percepts, and generate complex behaviors, is a fundamental challenge in neuroscience. To establish a link b...
We will show how to combine large scale neural recordings and mechanistic neural network models to advance our conceptual understanding of how neural circuits mediate cognitive functions lik...
Learning Objections: 1. To learn a new approach to understanding brain function by creating networks to perform tasks using machine learning. 2. To learn how how to probe these networks to d...
Learning Objectives: 1. Delineate the goals of studies of brain, computation and behavior and how they can be integrated. 2. Describe how neuromodulators such as oxytocin transform circuits...
Date: August 24, 2021 Time: 11:00am (PDT), 1:00pm (EDT) Electron-based dissociation mechanisms have shown great promise for advanced characterization of biomolecules. However, routine adopti...
Date: August 24, 2021 Time: 8:00am (PST), 11:00am (EST) Liver cancer is the third cause of cancer-related mortality worldwide. Most patients have chronic liver disease, which has allowed...
DATE: August 19, 2020 TIME: 8:00am PT, 11:00pm ET Type 2 diabetes mellitus (T2D) is associated with an increased risk of osteoporotic fractures. Several factors have been identified as being...
Date: August 17, 2021 Time: 1:00pm (PDT), 4:00pm (EDT) NovaFluor dyes are novel fluorophores for flow cytometry, designed with narrow emission spectra and minimal cross-laser excitation. Nov...
Date: August 11, 2021 Time: 8:00am (PDT), 11:00am (EDT) Procalcitonin (PCT) is a biomarker widely used to assess the risk of bacterial infection and to aid in antibiotic stewardship in patie...
Date: August 11, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Quality can never be assumed, is never automatic, and requires the long-term commitment of the laboratory, staff, and manufacturers. L...
Date: August 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The intrinsic emission of light by biological structures in the cells, known as autofluorescence (AF), can be detrimental for data reso...
Date: July 29, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Experts are predicting an increase in influenza cases and a constant presence of SARS-CoV-2 in the shortly approaching influenza season....
Date: July 29, 2021 Time: 1:00am (PDT), 4:00am (EDT) Traditionally limited to a small number of phenotypes and mutations suggested to specific risk groups, the emerging field of genomics i...